Award
NIH Reporter #5F31GM157882-02
Illuminating the Molecular Mechanisms of Replication and Transcription Coordination
Recipient
University of Pennsylvania
Award Amount
$49,538.00
Ceiling
$49,538.00
Awarded
February 13, 2026
Identifier
5F31GM157882-02
The University of Pennsylvania project studies how cells coordinate DNA replication and transcription, focusing on RNA polymerase II, PCNA, and the transcription factor Zelda. The award supports research using live imaging and single-molecule tracking to examine these processes in developing Drosophila embryos.
Description
Research project investigating how transcription and DNA replication are coordinated in developing Drosophila embryos, using live microscopy and single-molecule tracking to study the interactions and kinetics of transcription and replication proteins.