Award

NIH Reporter #1K99NS146570-01

Exploring Cholinergic Changes and their Associations with Sleep Alterations in the Lewy Body Disease Spectrum: New Biomarkers and Therapeutic Targets

Recipient

University of Michigan at Ann Arbor, MI

Award Amount

$128,358.00

Ceiling

$128,358.00

Awarded

February 16, 2026

Identifier

1K99NS146570-01

NIH funded research to study cholinergic changes affecting sleep in Lewy Body Disorders using imaging and wearable technology, aiming to develop biomarkers and treatments.

Description

This NIH grant project investigates the relationship between cholinergic brain changes and sleep alterations in Lewy Body Disorders, including Parkinson's disease and isolated REM sleep behavior disorder. The study uses advanced imaging techniques and wearable sleep recording devices to develop new biomarkers and therapeutic targets.

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