Award

Icahn School of Medicine at Mount Sinai 5F31AI191695-02

Separating the molecular determinants that govern the evolution of Orthoflavivirus NS5-mediated IFN antagonism

Recipient

Eva Bednarski

Award Amount

$49,114.00

Ceiling

$49,114.00

Awarded

June 12, 2026

Identifier

5F31AI191695-02

NIH-funded research project led by Eva Bednarski to study the molecular mechanisms of Orthoflavivirus NS5-mediated interferon antagonism, focusing on immune evasion and evolution, with a project duration of 2025-2028 and an award amount of approximately $49,114.

Description

Research project investigating the structural and functional determinants of NS5-mediated interferon antagonism in flaviviruses. Funded by NIH under FOA PA-23-272, aiming to expand understanding of flavivirus NS5-mediated immune evasion mechanisms and their evolution. Project duration is from June 1, 2025, to May 31, 2028, with Eva Bednarski as the primary investigator.

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