Award
National Institute on Aging 5R21AG082377-02
Submillimeter resolution diffusion MRI of the medial temporal lobe in the earliest stages of Alzheimer's disease
Recipient
Massachusetts General Hospital
Award Amount
$250,500.00
Ceiling
$250,500.00
Awarded
March 04, 2025
Identifier
5R21AG082377-02
This NIH grant funds the development of advanced diffusion MRI techniques to detect early neurodegeneration in Alzheimer's disease by focusing on the medial temporal lobe, aiming to provide early diagnostic biomarkers before irreversible neuronal loss occurs.
Description
Development of high-resolution and high-fidelity diffusion MRI acquisition technology tailored to the medial temporal lobe to overcome technical and physiological barriers and provide noninvasive diagnostic markers sensitive to very early microstructural and connectivity changes in Alzheimer's disease.