Award
National Cancer Institute 1DP2CA311216-01
Building a Systems Immunopeptidomics Framework to Challenge the Current T Cell Activation Paradigm
Recipient
Yale University
Award Amount
$1,512,500.00
Ceiling
$1,512,500.00
Awarded
August 07, 2025
Identifier
1DP2CA311216-01
This research project funded by the National Cancer Institute at Yale University seeks to challenge current paradigms of T cell activation by studying the self-immunopeptidome using advanced technologies, aiming to impact cancer immunotherapy and other immune-related therapies.
Description
The project aims to develop an innovative systems immunopeptidomics framework to investigate the regulatory role of self-peptides in T cell activation, with potential applications in cancer immunotherapy, autoimmune diseases, and vaccine development.