Award

Eunice Kennedy Shriver National Institute of Child Health and Human Development 5F31HD114456-02

Decoding Repression: Recruitment of epigenetic silencers by RNA binding proteins and long non-coding RNAs

Recipient

University of North Carolina at Chapel Hill

Award Amount

$41,204.00

Ceiling

$41,204.00

Awarded

December 05, 2025

Identifier

5F31HD114456-02

NIH awarded $41,204 to University of North Carolina at Chapel Hill for a project decoding epigenetic silencing mechanisms via RNA binding proteins and long non-coding RNAs, focusing on RNA biochemistry and genomics.

Description

The project focuses on gene expression regulation via long non-coding RNAs and epigenetic mechanisms. The award is for a multiyear project with a focus on RNA biochemistry, genomics, and computational biology. The project involves studying the recruitment of epigenetic modifiers by RNA, specifically Xist and hnRNPK. The funding is from NIH, with a total award of $41,204 for FY 2026. The project aims to define RNA sequence features and molecular interactions involved in epigenetic silencing.

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