Award
NIH Reporter #5R01HL166246-04
Coagulation Factor XII Recruitment and Activation During Thrombus Formation
Recipient
National Heart Lung and Blood Institute (NHLBI)
Award Amount
$678,684.00
Ceiling
$678,684.00
Awarded
June 10, 2026
Identifier
5R01HL166246-04
NIH awarded a research grant to study coagulation factor XII's role in thrombus formation, aiming to develop new therapeutics. The project is funded for $678,684 and spans multiple years.
Description
NIH research grant opportunity focused on the molecular mechanisms of coagulation factor XII (FXII) recruitment, activation, and propagation at the platelet surface. The project aims to develop novel therapeutics based on FXII blockade. The award is for a multi-year project with a total funding of approximately $678,684 for FY 2026. The project involves structural studies, mapping of FXII domains, and in vivo thrombosis models.