Award
National Institute of Arthritis and Musculoskeletal and Skin Diseases 5R01AR075121-05
Intra-cartilage depot delivery of electrically-charged IL-1RA for targeting osteoarthritis-associated inflammation and catabolism in multiple joint tissues
Recipient
Northeastern University
Award Amount
$383,356.00
Ceiling
$383,356.00
Awarded
September 21, 2020
Identifier
5R01AR075121-05
Award for research project developing electrically charged IL-1RA to improve osteoarthritis drug delivery and treatment effectiveness.
Description
The project focuses on developing electrically charged IL-1RA for osteoarthritis treatment. The project involves modifying a promising OA drug to enhance cartilage penetration and retention. The work aims to enable clinical translation of osteoarthritis drugs with improved delivery techniques.