Award
National Heart, Lung, and Blood Institute 5R01HL181370-02
Erythroblastic island macrophages in normal erythropoiesis and disordered erythropoiesis in polycythemia vera
Recipient
New York Blood Center, New York, NY, United States
Award Amount
$785,595.00
Ceiling
$785,595.00
Awarded
May 05, 2026
Identifier
5R01HL181370-02
The project investigates how central macrophages support erythropoiesis and how JAK2 mutations contribute to red blood cell overproduction in polycythemia vera, aiming to define mechanisms and explore therapeutic targets.
Description
This NIH-funded project focuses on understanding the role of macrophages in erythropoiesis and the impact of JAK2 mutations in polycythemia vera, aiming to identify new therapeutic targets and improve treatment strategies.