# NIH Reporter #11311406

Improving Human Hematopoietic Progenitor Cell Cryopreservation using Anti-aging, Nature-inspired and Stress Modulation Formulations

**Recipient:** CELL PRESERVATION SERVICES, INC.

**Award Amount:** $314,400.00
**Ceiling:** $314,400.00

**Awarded:** September 16, 2026

**Identifier:** 11311406

Award for developing non-toxic cryoprotective agents to improve hematopoietic stem cell preservation, replacing DMSO and enhancing cell viability, under the SBIR program.

### Description

The project focuses on developing non-toxic cryoprotective agents for hematopoietic stem cells, aiming to replace DMSO and improve post-thaw cell viability and function. It includes formulation of a cryococktail (Chillout-HC) and a CP dilution reagent (RevitalICE-HC), with a focus on reducing toxicity and addressing cellular aging effects. The project is part of the SBIR program and aims to create a commercially viable, FDA-acceptable cryopreservation solution. It involves in vivo studies and aims to eliminate DMSO toxicity in stem cell cryopreservation.

[View original record](https://reporter.nih.gov/search/IgE1H2ioLUOz0qmA4MDg0Q/project-details/11311406)