Award
National Cancer Institute 5P01CA084203-20
Project 2: Intratumoral PDT Induces PDP-based Enhancement of PD-1 Inhibition in Pancreatic Carcinoma
Recipient
Massachusetts General Hospital
Award Amount
$218,467.00
Ceiling
$218,467.00
Awarded
March 06, 2026
Identifier
5P01CA084203-20
This award funds a project to improve immune response in pancreatic cancer by combining photodynamic priming and PD-1 inhibition therapy.
Description
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer. The project aims to enhance immune response using photodynamic priming (PDP) with Verteporfin and light, followed by immune checkpoint inhibitor therapy. The project involves advanced imaging, immune response assessment, and combination therapy in pancreatic cancer.