Award
National Institute of Arthritis and Musculoskeletal and Skin Diseases 5R01AR078306-05
Transposable elements in the keratinocyte genome and their regulation during skin development and epidermal differentiation
Recipient
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Award Amount
$456,155.00
Ceiling
$456,155.00
Awarded
December 23, 2024
Identifier
5R01AR078306-05
NIH grant awarded to study epigenetic regulation of transposable elements in keratinocytes related to skin development and inflammatory conditions.
Description
This NIH-funded project investigates the epigenetic regulation of transposable elements in keratinocytes, aiming to elucidate mechanisms underlying skin development, homeostasis, and inflammatory skin conditions such as psoriasis and lupus erythematosus. The project involves defining TE expression landscapes, roles of epigenetic regulators, and impacts on inflammatory responses, with a focus on therapeutic interventions for skin disorders.