Award
National Institute of Mental Health 2R15MH101703-04A1
Investigating the roles of UBE3A and TRPML1 in extracellular vesicle regulation to understand Angelman syndrome pathogenesis
Recipient
Western University of Health Sciences, Pomona, CA, United States
Award Amount
$429,000.00
Ceiling
$429,000.00
Awarded
June 19, 2025
Identifier
2R15MH101703-04A1
A research project funded by the National Institute of Mental Health to study the molecular roles of UBE3A and TRPML1 in extracellular vesicle regulation related to Angelman syndrome, aiming to find therapeutic interventions.
Description
This project investigates the roles of UBE3A and TRPML1 in brain development via extracellular vesicles to understand Angelman syndrome pathogenesis. The study aims to elucidate molecular mechanisms underlying neurodevelopmental disorders and explore extracellular vesicles as potential therapeutic tools and biomarkers.