Award

NIH Reporter #2R01NS072381-15A1

Study of the Cellular Basis of Herpes Simplex Encephalitis with hPSC-Derived CNS and PNS Cells

Recipient

UT SOUTHWESTERN MEDICAL CENTER

Award Amount

$672,898.00

Ceiling

$672,898.00

Awarded

August 12, 2026

Identifier

2R01NS072381-15A1

This award funds a research project at UT Southwestern Medical Center to study the cellular and genetic mechanisms of Herpes Simplex Encephalitis using advanced stem cell models, aiming to improve understanding of CNS immunity to HSV-1.

Description

Research project focused on analyzing the cellular basis of Herpes Simplex Virus 1 (HSV-1) encephalitis using peripheral nervous system and central nervous system cells derived from human induced pluripotent stem cells. The study aims to elucidate genetic and cellular mechanisms underlying HSV-1 infection and immunity.

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