Award
National Eye Institute 5K99EY037374-02
Transformations of photic information in melanopsin pathways
Recipient
Boston Children's Hospital
Award Amount
$136,512.00
Ceiling
$136,512.00
Awarded
July 22, 2026
Identifier
5K99EY037374-02
Research project funded by the National Eye Institute to study how melanopsin pathways transform photic information affecting physiology and behavior, focusing on mechanisms underlying the pupil light reflex and potential therapeutic applications.
Description
This project concerns the generation and transformation of information that drives vital effects of light on physiology and behavior. The experiments will define how properties of light-evoked behavior, such as the pupil light reflex, emerge from mechanisms in photoreceptor cells and downstream brain transformations. Insights from this research may help develop therapeutics for disruptions in light regulation affecting circadian rhythms, mood, and sleep.