Award
National Institute of Arthritis and Musculoskeletal and Skin Diseases 5P50AR080612-04
A platelet-fibroblast axis connecting bioenergetics and metabolism in SSc-pulmonary arterial hypertension
Recipient
University of Pittsburgh at Pittsburgh
Award Amount
$234,488.00
Ceiling
$234,488.00
Awarded
September 19, 2025
Identifier
5P50AR080612-04
Research project focused on understanding vascular cell communication and developing diagnostic imaging techniques for systemic sclerosis-related pulmonary arterial hypertension.
Description
This project aims to define how cells in the blood vessels in the lung from persons who suffer from systemic sclerosis communicate with each other and promote the development of disease in those blood vessels. It includes a first-in-human study to define a new imaging technique for better detection of blood vessel disease in lungs, potentially shaping principles of disease development and offering improved detection and treatment methods for systemic sclerosis-related pulmonary arterial hypertension.