Award
National Institute of Allergy and Infectious Diseases 5R01AI173778-04
Tegument Envelope Protein Interactions in CMV Envelopment
Recipient
University of Alabama at Birmingham
Award Amount
$481,131.00
Ceiling
$481,131.00
Awarded
January 07, 2026
Identifier
5R01AI173778-04
Research project funded by NIAID to study human cytomegalovirus protein interactions during virus envelopment to support antiviral and vaccine development.
Description
This project aims to identify interactions between viral proteins during virus envelopment to define mechanisms that could aid in antiviral therapeutic development and vaccine improvement. It studies interactions between glycoprotein complexes and membrane proteins involved in virion envelopment, using recombinant viruses with specific mutations to understand virion assembly and identify potential therapeutic targets.