Award
National Institute of Neurological Disorders and Stroke 5R01NS129784-04
Deciphering brain mosaicism in drug-resistant epilepsy at cellular resolution
Recipient
Research Institute Nationwide Children's Hospital
Award Amount
$544,016.00
Ceiling
$544,016.00
Awarded
January 31, 2026
Identifier
5R01NS129784-04
Award for research on brain mosaicism in drug-resistant epilepsy to improve somatic variant detection and develop targeted treatments, funded by NINDS.
Description
The project aims to improve somatic variant detection in malformations of cortical development using advanced techniques such as integrated single-nuclei genotyping and transcriptomics. The research is significant for developing targeted treatments for drug-resistant epilepsy. Funding is provided by the NIH, specifically the National Institute of Neurological Disorders and Stroke (NINDS). The project duration is from March 1, 2023, to December 31, 2027.