Award
NIH Reporter #5R33GM151703-04
Leveraging multi-omics to maximize the scientific value of pediatric sepsis biorepository and advance patient endotyping
Recipient
Cincinnati Children's Hospital Medical Center
Award Amount
$697,828.00
Ceiling
$697,828.00
Awarded
June 25, 2026
Identifier
5R33GM151703-04
This award supports research using multi-omics to study pediatric sepsis, aiming to classify patient endotypes and improve targeted treatments.
Description
The project aims to use multi-omics approaches, including DNA methylation profiling and RNA sequencing, to explore the scientific value of biospecimens from critically ill children with sepsis. The goal is to identify biologically relevant endotypes, develop classifiers for patient stratification, and inform targeted therapeutics.