Award
National Institute of Allergy and Infectious Diseases 1R21AI191344-01A1
Peptide-conjugated phosphodiamidate morpholino oligonucleotide (PPMO)-based henipavirus therapeutics
Recipient
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
Award Amount
$475,339.00
Ceiling
$475,339.00
Awarded
March 30, 2026
Identifier
1R21AI191344-01A1
Award for developing PPMO-based therapeutics targeting henipavirus, including design, testing, and in vivo studies in hamsters.
Description
This project involves developing peptide-conjugated phosphorodiamidate morpholino oligomers (PPMO) as therapeutics against Nipah virus. The project includes design, in vitro testing, mechanism of action studies, and in vivo testing in a hamster model.