Award
National Institute of Biomedical Imaging and Bioengineering 5R01EB036987-02
AI-assisted quantitative photon-counting-detector CT imaging for cytogenetic risk prediction and treatment response in multiple myeloma
Recipient
Mayo Clinic Rochester
Award Amount
$592,998.00
Ceiling
$592,998.00
Awarded
January 30, 2026
Identifier
5R01EB036987-02
Development of AI-assisted photon-counting-detector CT imaging to improve cytogenetic risk prediction and treatment response assessment in multiple myeloma, aiming to replace invasive bone marrow biopsies with noninvasive imaging biomarkers.
Description
This project will develop a new low-dose CT imaging technique to quantitatively identify response to multiple myeloma therapy, stratify cytogenetic risk, and provide prognostic models, which will guide treatment choices. The project aims to establish CT imaging as a noninvasive pathway to measure changes in the activity of multiple myeloma disease after therapy and eliminate the need for routine invasive bone marrow biopsies.