Award
University of Minnesota 5R35GM153306-03
Chemical Strategies to Map Bacterial Response to Environmental Change
Recipient
University of Minnesota
Award Amount
$542,775.00
Ceiling
$542,775.00
Awarded
May 21, 2026
Identifier
5R35GM153306-03
Award to University of Minnesota for developing chemical tools to study bacterial cell wall synthesis and signal transduction, with a focus on histidine kinases and penicillin-binding proteins, aiming to support anti-virulence strategies.
Description
This grant aims to develop chemical tools to understand bacterial cell wall synthesis and signal transduction, focusing on histidine kinases and penicillin-binding proteins. The project involves expanding chemical probe libraries, optimizing delivery into bacteria, and validating targets for anti-virulence strategies.