Award
National Institute of Mental Health 5R01MH126911-05
Integrated Reward-Circadian Rhythm Model of First Onset of Bipolar Spectrum Disorders in Adolescence
Recipient
Temple University of the Commonwealth
Award Amount
$711,224.00
Ceiling
$711,224.00
Awarded
July 29, 2025
Identifier
5R01MH126911-05
A NIH grant awarded to study the relationship between circadian rhythms and reward processing in the onset of bipolar spectrum disorders in adolescents, aiming to develop targeted interventions.
Description
This project will examine bidirectional relationships between circadian and reward function at multiple levels of analysis and their joint prediction of first onset of bipolar spectrum disorders (BSD) and increases in hypomanic/manic and depressive symptoms. It aims to identify vulnerabilities, understand etiological pathways, and develop interventions for reward processing and circadian rhythm abnormalities contributing to BSDs.