Award
NIH Reporter #5U01AI169385-05
Defining the mechanisms of HIV resistance to bNAbs in humans
Recipient
Rockefeller University, New York, NY, United States
Award Amount
$1,569,774.00
Ceiling
$1,569,774.00
Awarded
May 01, 2026
Identifier
5U01AI169385-05
Research project funded by NIH to study HIV-1 resistance mechanisms to broadly neutralizing antibodies to improve therapeutic strategies.
Description
This project aims to understand the diversity of pathways leading to HIV-1 resistance to broadly neutralizing antibodies (bNAbs) in humans. It involves deep sequencing, mapping resistance mutations, analyzing resistant variants, and developing computational models to inform the design of effective bNAb combinations.