Award
Utah Department of Veterans and Military Affairs 5I01RX003911-04
Fluoridated scaffolds for the treatment of critical-size bone defects
Recipient
VA SALT LAKE CITY HEALTHCARE SYSTEM, SALT LAKE CITY, UT, UNITED STATES
Awarded
May 01, 2026
Identifier
5I01RX003911-04
Development of fluoridated bone scaffolds combined with stem cells to repair critical-size bone defects, aiming to provide an off-the-shelf autograft-like solution for bone regeneration, funded by VA and NIH.
Description
The project aims to develop off-the-shelf autograft-like bone scaffolds using fluoridated calcium phosphate bioceramics combined with stromal vascular fraction cells from autologous fat tissue, to treat critical-size bone defects. The study includes multiple specific aims involving animal models and mechanistic studies. The project is funded by VA and NIH grants, with a focus on bone regeneration and orthopedic applications.