Award
NIH Reporter #PA-25-301
Synergistic Effects of Unacylated Ghrelin and Endurance Exercise on Sarcopenia and Mobility Loss
Recipient
Bumsoo Ahn
Award Amount
$711,218.00
Ceiling
$711,218.00
Awarded
January 29, 2026
Identifier
PA-25-301
This NIH grant awarded by the National Institute on Aging supports research on the combined effects of unacylated ghrelin and endurance exercise to combat sarcopenia and mobility loss in aging, aiming to improve muscle and neuromuscular health over a 5-year period.
Description
The project focuses on enhancing training responses in older mice using endurance exercise combined with unacylated ghrelin. It aims to improve mitochondrial bioenergetics, muscle mass, and neuromuscular junction integrity. The project is aligned with the NIA's strategic direction to develop effective interventions for age-related diseases and involves transcriptomic analysis to identify gene pathways affected by the intervention.