Award
National Institute of Neurological Disorders and Stroke 5R01NS076511-14
Lipid Imaging in Traumatic Brain Injury by High Resolution GCIB-secondary Ion Mass Spectrometry
Recipient
Columbia University Health Sciences
Award Amount
$602,698.00
Ceiling
$602,698.00
Awarded
July 29, 2026
Identifier
5R01NS076511-14
Award for research on high-resolution lipid imaging in traumatic brain injury using advanced SIMS technology to study cell death mechanisms and develop targeted therapies.
Description
This project aims to optimize and apply revolutionary multi-omics imaging technology based on secondary ion mass spectrometry (SIMS) to achieve high-resolution, simultaneous imaging of lipids, proteins, and metabolites in brain tissues. The goal is to identify cell types involved in ferroptosis, a regulated cell death process driven by lipid peroxidation, and to develop targeted therapies for traumatic brain injury (TBI).