Award
National Heart, Lung, and Blood Institute 11166357
Roles of Red Blood Cell Derived Extracellular Vesicles in Complement Activation and Thromboinflammation in Sickle Cell Disease
Recipient
University of Houston
Award Amount
$106,486.00
Ceiling
$106,486.00
Awarded
August 19, 2025
Identifier
11166357
Research project funded by NHLBI to study red blood cell derived extracellular vesicles in sickle cell disease, focusing on complement activation and thromboinflammation using microfluidic systems.
Description
This project aims to investigate the roles of extracellular vesicles (REVs) derived from red blood cells in complement activation and thromboinflammation in sickle cell disease (SCD). The research will utilize microfluidic systems and functional assays to evaluate REVs as biomarkers for disease activity and response to therapy.