Award
National Institute of Allergy and Infectious Diseases 1R01AI198555-01
Enhancing T and B cell responses to Plasmodium via IL-15
Recipient
HENNEPIN HEALTHCARE RESEARCH INSTITUTE, MINNEAPOLIS, MN, UNITED STATES
Award Amount
$661,037.00
Ceiling
$661,037.00
Awarded
May 01, 2026
Identifier
1R01AI198555-01
A research project funded by NIAID to develop IL-15 based immunotherapy to enhance T and B cell responses to malaria, improving vaccine efficacy and immune durability.
Description
This project investigates an IL-15 cytokine-based therapy to enhance immune responses to Plasmodium infection and vaccination, aiming to improve vaccine efficacy and immune durability. It focuses on promoting T follicular helper cells and liver-resident memory T cells to improve vaccine responses against malaria.