Award
National Institute of Allergy and Infectious Diseases 5R01AI188782-02
pH-Dependent Switching of ESX-1 Substrates in Mycobacterial Pathogenesis
Recipient
University of Notre Dame
Award Amount
$737,391.00
Ceiling
$737,391.00
Awarded
August 04, 2026
Identifier
5R01AI188782-02
NIH multi-year grant awarded to study molecular mechanisms of mycobacterial pathogenesis related to ESX-1 substrate switching influenced by pH, aiming to uncover virulence mechanisms and infection biology insights.
Description
The project focuses on understanding the molecular mechanisms of mycobacterial pathogenesis, specifically ESX-1 substrate switching in response to pH. The research aims to identify virulence mechanisms and provide insights into infection biology.