Award
National Eye Institute 5R01EY024590-11
Identification of optimum spectacle prescriptions for patients with Down syndrome
Recipient
Ohio State University, Columbus, OH, United States
Award Amount
$392,417.00
Ceiling
$392,417.00
Awarded
July 14, 2025
Identifier
5R01EY024590-11
The award funds a project to develop and test improved spectacle prescriptions for children with Down syndrome using objective refraction methods to enhance visual acuity and independence.
Description
This project aims to test new objective spectacle prescribing strategies to improve visual quality for individuals with Down syndrome (DS). It focuses on measuring visual and retinal image quality to identify optimal sphere and cylinder corrections, with the goal of achieving multi-line acuity gains over traditional corrections. The work involves a randomized treatment trial comparing three refractive methods in children with DS, addressing barriers to multi-line acuity improvements, and optimizing objective refraction processes. The ultimate goal is to enhance visual performance, foster independence, and apply findings to other populations unable to participate in subjective refractions.