NIH Reporter #1R56NS147432-01A1

The role of Renshaw cells and recurrent inhibition during motor behaviors

Research project funded by NINDS to study the role of Renshaw cells in motor behaviors, aiming to understand their function in motor control and dysfunction using advanced neurophysiological techniques and animal models.

Description

This project investigates the function of Renshaw cells, key inhibitory interneurons in the spinal cord, to reveal their roles during normal and abnormal motor function. It aims to analyze their roles in motor unit recruitment, spike timing, muscle activation, and co-contraction during postural adjustments using advanced mouse models and multielectrode arrays. The project will contribute to understanding motor control and dysfunction, potentially impacting treatments for motor disorders.

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