Award
National Center for Advancing Translational Sciences 1R43TR005424-01
A Novel Approach to Eliminate Length Impurities for High-Quality mRNA Production
Recipient
Not specified
Award Amount
$349,746.00
Ceiling
$349,746.00
Awarded
July 17, 2025
Identifier
1R43TR005424-01
Award for developing a novel method to produce high-quality mRNA free of length impurities, funded by NIH's NCATS under the SBIR program.
Description
The project involves developing and validating a production method for high-quality, impurity-free mRNA. The award is part of NIH's SBIR program, focusing on innovative biopharmaceutical manufacturing. The project aims to eliminate impurities such as dsRNA, LRNA, and stRNA, and validate the technology in mice. The project duration is from August 1, 2025, to July 31, 2027.