Award
National Institute of Environmental Health Sciences 5R01ES026673-09
Contaminant Metal Content in Wildfire Smoke and Neuroinflammation
Recipient
University of New Mexico Health Sciences Center
Award Amount
$590,673.00
Ceiling
$590,673.00
Awarded
December 30, 2025
Identifier
5R01ES026673-09
Research project funded by NIEHS to study the effects of metal-contaminated wildfire smoke on neuroinflammation and potential therapeutic approaches, with a focus on populations near uranium mine sites in New Mexico.
Description
This project investigates the toxicity of metals in biomass smoke, the role of cerebrovascular adhesion molecules in neuroinflammation, and mechanisms of neuroinflammatory resolution, including potential therapeutic strategies using lipid mediators. It involves laboratory-based inhalation studies to assess the impact of metal-contaminated biomass smoke on pulmonary and neurovascular health, focusing on vulnerable populations near abandoned uranium mine sites in New Mexico.