Award
National Institute of Arthritis and Musculoskeletal and Skin Diseases 3R01AR077760-05S1
Anti-inflammatory Cell Based Repair of Intervertebral Disc Degeneration
Recipient
Columbia University Health Sciences
Award Amount
$94,525.00
Ceiling
$94,525.00
Awarded
August 12, 2025
Identifier
3R01AR077760-05S1
The award supports research to improve regenerative therapies for intervertebral disc degeneration by enhancing anti-inflammatory responses and mechanical loading effects on mesenchymal stem cells and macrophages to promote tissue repair.
Description
This project aims to develop regenerative therapies for disc degeneration by modulating inflammatory responses and mechanical loading to enhance tissue repair. The research focuses on the role of mesenchymal stem cells and macrophages in immunomodulation and tissue repair in the intervertebral disc.