Award
National Institute of General Medical Sciences 5R35GM160071-02
Viral Biosensors of Host Post-Translational Modifications
Recipient
University of California Los Angeles
Award Amount
$420,984.00
Ceiling
$420,984.00
Awarded
July 07, 2026
Identifier
5R35GM160071-02
NIH funded research project to study viral biosensors of host post-translational modifications to identify new antiviral targets.
Description
This research aims to understand how viruses sense, respond, and adapt to their hosts through host-derived post-translational modifications, creating viral proteoforms with multifunctionality. The study focuses on PTMs such as phosphorylation at key sites on viral proteins, which may regulate viral functions and interactions with host immune responses. The project investigates how viruses navigate host cellular locations, coordinate with the host cell cycle, and exploit innate immune mechanisms, with the goal of identifying new antiviral targets.