Award
National Institute of Diabetes and Digestive and Kidney Diseases 1DP2DK143367-01
The Circadian Clock Coordinates Animal and Microbial Metabolism
Recipient
Princeton University
Award Amount
$1,457,999.00
Ceiling
$1,457,999.00
Awarded
September 04, 2024
Identifier
1DP2DK143367-01
This NIH-funded project studies how circadian clocks coordinate metabolism between animals and their microbiomes to promote health, using interdisciplinary methods.
Description
The project aims to mechanistically determine how circadian clocks synchronize animal and microbial metabolic activities to promote overall health and fitness. It investigates how circadian clocks and feeding rhythms influence microbiome composition and function, and how these oscillations impact host physiology. The research employs interdisciplinary approaches including metabolomics, gnotobiotic mouse models, and bacterial genetics.