Award
NIH Reporter #1R21AI193256-01A1
Determining the role for lncRNAs in TB infection in macrophages
Recipient
UNIVERSITY OF CALIFORNIA SANTA CRUZ
Award Amount
$259,415.00
Ceiling
$259,415.00
Awarded
September 02, 2026
Identifier
1R21AI193256-01A1
A NIH-funded research project led by Dr. Susan Carpenter at UC Santa Cruz to study the role of lncRNAs in macrophage response to tuberculosis infection, aiming to identify new therapeutic targets through advanced genetic screening techniques.
Description
This research grant aims to identify and understand the role of long non-coding RNAs (lncRNAs) in the macrophage response to Mycobacterium tuberculosis (Mtb) infection, with the goal of finding new therapeutic targets. The project uses innovative high-throughput screening and CRISPRi libraries to study lncRNAs' involvement in regulating inflammation and bacterial replication during tuberculosis infection.