# NIH Reporter #1F32EY038566-01A1

Deciphering the role of cellular and physiological mechanisms in glaucoma via integrative genomics, imaging, and computational modeling

**Recipient:** Massachusetts Eye and Ear Infirmary

**Award Amount:** $76,780.00
**Ceiling:** $76,780.00

**Awarded:** September 14, 2026

**Identifier:** 1F32EY038566-01A1

The National Eye Institute-funded project studies genetic, cellular, and vascular mechanisms of primary open-angle glaucoma using genomic data, fundus imaging, and computational blood-flow models, with the goal of better identifying disease subtypes and informing personalized therapies.

### Description

Research project integrating cell type-specific polygenic risk scores, eye-tissue multi-omics, ocular imaging, and computational modeling of retinal blood flow to investigate cellular and physiological mechanisms underlying primary open-angle glaucoma and support improved diagnosis and targeted treatments.

[View original record](https://reporter.nih.gov/search/J7l2tQ4hHkqRePwGq3m5kA/project-details/11461664)