Award
Eunice Kennedy Shriver National Institute of Child Health and Human Development 5R01HD109152-05
Signaling mechanisms that modulate uterine 3D structure for pregnancy success
Recipient
Michigan State University, East Lansing, MI
Award Amount
$363,136.00
Ceiling
$363,136.00
Awarded
June 09, 2026
Identifier
5R01HD109152-05
Research grant to study how progesterone and embryo signals affect uterine 3D structure to improve pregnancy success, using imaging and analysis in mouse models and humans.
Description
This project aims to investigate the mechanisms by which progesterone and embryo signals influence the 3D structure of the uterus to facilitate successful implantation and pregnancy. Using confocal imaging and 3D analysis in mouse models and human subjects, the study will explore how uterine folding is regulated developmentally and hormonally, and how abnormalities in structure may lead to adverse pregnancy outcomes.