Award

NIH Reporter #1R21AG091290-01A1

Neurocognitive Dysfunction in Adrenal Cortisol Insufficiency

Recipient

Cedars-Sinai Medical Center, Los Angeles, CA, United States

Award Amount

$419,321.00

Ceiling

$419,321.00

Awarded

September 08, 2025

Identifier

1R21AG091290-01A1

A research project funded by the National Institute on Aging to study neurocognitive dysfunction in adrenal cortisol insufficiency, comparing subtypes PACI and SACI to controls to improve understanding and management.

Description

The study aims to define neurocognitive profiles in primary and secondary adrenal cortisol insufficiency (ACI) using NIH Toolbox Cognitive Battery and patient-reported outcomes. It will compare neurocognitive function in PACI and SACI subtypes to controls, providing an evidence base for larger clinical trials and potential integration of neurocognitive testing into routine management.

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