Award
NIH Reporter #5K23NS123429-05
Integrating brain and behavioral measures of central pain inhibition to personalize treatment in chronic pain management
Recipient
University of Pittsburgh at Pittsburgh
Award Amount
$183,791.00
Ceiling
$183,791.00
Awarded
February 24, 2026
Identifier
5K23NS123429-05
The project focuses on defining changes in central pain inhibition in chronic pain patients using novel brain and behavioral tools to personalize treatment and improve patient outcomes.
Description
This project aims to improve chronic pain treatment by examining the contribution of central pain inhibition to chronic pain and patient-to-patient heterogeneity of treatment response. It uses novel brain and behavioral measures to predict treatment response to established analgesics, personalizing chronic pain management and allowing the study of novel analgesics in phenotypically-defined patient populations.