Award
National Heart, Lung, and Blood Institute 5R01HL174024-02
ILC2s as drivers of lung dysfunction in response to early-life inflammation
Recipient
Utah State Higher Education System--University of Utah
Award Amount
$704,005.00
Ceiling
$704,005.00
Awarded
July 24, 2026
Identifier
5R01HL174024-02
NIH funded research project awarded to University of Utah to study the role of ILC2 cells in lung dysfunction and asthma susceptibility related to early-life inflammation, with a total award amount of $704,005.
Description
The project focuses on the role of ILC2 cells in asthma susceptibility related to early-life infections. The research aims to define cellular and molecular mechanisms, test necessity and sufficiency of ILC2s, and investigate human cord blood ILC2s. The project involves advanced techniques such as single-cell transcriptomics, ATAC-seq, and adoptive transfer assays. It aims to identify new therapeutic targets for asthma prevention and treatment.