Award

National Institute of Diabetes and Digestive and Kidney Diseases 5U01DK135017-04

Integrative analysis of multi-omic signatures and cellular function in human pancreas across developmental timeline at single-cell spatial resolution

Recipient

Vanderbilt University Medical Center, Nashville, TN, United States

Award Amount

$799,570.00

Ceiling

$799,570.00

Awarded

August 12, 2025

Identifier

5U01DK135017-04

This NIH-funded project aims to understand pediatric pancreas development and β cell maturation using advanced multi-omic and spatial analysis techniques to inform diabetes research and therapy development.

Description

Studies of human pancreas development focusing on molecular and cellular processes during the pediatric period to improve diagnosis and treatment of type 1 and type 2 diabetes. The project uses single-cell multi-omic spatially-resolved data and living slice technology to investigate β cell maturation and pancreatic architecture.

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