# NIH Reporter #1F31MH145830-01

Loss of Conserved Regulatory Elements in Human Brain Evolution

**Recipient:** University of Alabama at Birmingham

**Award Amount:** $41,809.00
**Ceiling:** $41,809.00

**Awarded:** August 11, 2026

**Identifier:** 1F31MH145830-01

Research project funded by NIH/NIMH to study the impact of conserved regulatory element loss on human brain evolution and neurological disorders, with a total award amount of $41,809 spanning 2026 to 2029.

### Description

This project investigates how the loss of deeply conserved gene regulatory elements shaped human brain evolution and contributes to neurological disorders such as autism and epilepsy. It involves integrating evolutionary genomics, high-throughput functional assays, and human genetic data to identify regulatory variants that alter brain development.

[View original record](https://reporter.nih.gov/search/0C83gI3MXki4-tEhFD4UKQ/project-details/11458751)