# NIH Reporter #1R01DK149654-01

Targeting Intracellular CD38 to Reduce Ischemia-Reperfusion Injury in Liver Transplantation

**Recipient:** Ohio State University

**Award Amount:** $807,563.00
**Ceiling:** $807,563.00

**Awarded:** August 24, 2026

**Identifier:** 1R01DK149654-01

The project will study how type III CD38 contributes to liver ischemia-reperfusion injury, develop selective inhibitors, and evaluate their effectiveness in animal models and human liver tissue.

### Description

Research award to investigate and develop selective type III CD38 inhibitors to reduce ischemia-reperfusion injury and improve donor liver function in transplantation.

[View original record](https://reporter.nih.gov/search/7U_RDKopbE--cH-2OrGcnA/project-details/11465898)