Award
NIH Reporter #5F31NS145736-02
Characterizing EZH1 Gain of function mutations to understand neurodevelopmental disease and inform EZH1-inhibitor innovation
Recipient
University of Pennsylvania
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
August 21, 2026
Identifier
5F31NS145736-02
Research project funded by NINDS to study EZH1 gain-of-function mutations in neurodevelopmental disorders and develop EZH1-specific inhibitors.
Description
This project aims to elucidate the role of EZH1 mutations in neurodevelopmental disorders and explore targeted inhibitors as potential therapies. The research will include advanced imaging, molecular methodologies, and rigorous experimental design.