Award

National Heart, Lung, and Blood Institute 7R21HL169555-02

Chronic dehydration in sickle cell disease: An actionable biomarker to prevent vaso-occlusive episodes

Recipient

Johns Hopkins University, Baltimore, MD

Award Amount

$131,050.00

Ceiling

$131,050.00

Awarded

August 20, 2025

Identifier

7R21HL169555-02

Award for research on chronic dehydration in sickle cell disease to identify biomarkers for preventing vaso-occlusive episodes, aiming to improve patient care through hydration monitoring.

Description

This project involves epidemiologic and clinical studies on dehydration in sickle cell disease, utilizing serum osmolality assays and data from NIH cohorts. The goal is to determine if chronic dehydration predicts morbidity and mortality, potentially influencing patient care and hydration monitoring practices.

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