Award
NIH Reporter #5R01GM118847-09
Cell signaling through O-GlcNAc reader proteins
Recipient
Duke University, Durham, NC
Award Amount
$319,472.00
Ceiling
$319,472.00
Awarded
August 12, 2025
Identifier
5R01GM118847-09
Research project funded by the National Institute of General Medical Sciences to study O-GlcNAc-mediated protein interactions and their role in cell signaling and disease.
Description
This project investigates the biochemical and physiological roles of O-GlcNAc modifications and their interactions with specific proteins, aiming to advance understanding of intracellular signaling pathways and disease mechanisms. The work may reveal new therapeutic opportunities to treat diseases where glycosylation is dysregulated, including cancer, diabetes, and neurodegeneration.