NIH Reporter #3R01HD115466-01A1S2

Advancing neurodevelopmental outcome prediction in children exposed to HIV using clinical features and placental imaging

A research project funded by NICHD to enhance prediction of neurodevelopmental outcomes in HIV-exposed children using clinical and placental imaging data, employing AI and advanced analysis methods.

Description

This project aims to improve neurodevelopmental outcome prediction in children exposed to HIV by integrating clinical features and placental imaging data. The study leverages a multi-country birth cohort and linked placental biobank, employing advanced 3D stereology and AI classifier models to identify placental abnormalities associated with adverse child health outcomes. The research involves causal inference and mediation analysis to understand the mechanisms linking placental features to neurodevelopmental and growth outcomes.

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